PAGET'S DISEASE

PAGET'S DISEASE

DEFINITION:-

It is a chronic skeletal disorder resulting from excessive osteoclast activity, mostly affecting the long bones and skull, backbone, pelvis.

CAUSES:-

  • Unknown cause but some risk-factors are there
  • Family history
  • More common in man then woman
  • Age above 40 years.


SIGNS AND SYMPTOMS:-

  • Generally asymptomatic
  • Pain
  • Fracture
  • Paget's lesions, may lead to osteoarthritis joint destruction
  • Hearing problem due to skull enlargement
  • Tinnitus
  • Vertigo
  • Bone tumour.


DIAGNOSTIC FINDING:-

  • Physical examination
  • X-ray
  • Bone biopsy
  • Bone scan show paget's activity.


MEDICAL MANAGEMENT:-

  • Bone resorption antagonist, e.g., biphosphate (risedronate, pamidronate)
  • Antineoplastic agent, e.g., plicamycin
  • Analgesics to relieve pain.


NURSING MANAGEMENT:-

Nursing Diagnosis

  • Chronic pain related to disease process.
  • Risk for injury related to falls.

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